Biocompatibility of fluids for multiphase drops-in-drops microfluidics

Biocompatibility of fluids for multiphase drops-in-drops microfluidics

This paper addresses the biocompatibility of fluids and surfactants in the context of microfluidics and more specifically in a drops-in-drops system for mammalian cell based drug screening. In the drops-in-drops approach, three immiscible fluids are used to manipulate the flow of aqueous microliter-sized drops; it enables merging of drops containing cells with drops containing drugs within a Te...

Ascending motion of drops in stratified fluids

In this paper, we examine spatio-temporal evolution of free moving drops in a vertically stratified fluid and study the role of stratification on the rise velocity of a single drop, two drops and a swarm of rising drops. Utilizing fully resolved three-dimensional Direct Numerical Simulations (DNS), we discuss the effects of density stratification on the interaction of two drops and microstructu...

“ Dripping , Jetting , Drops and Wetting : The Magic of Microfluidics ”

The following article is based on the Symposium X presentation given by David A. Weitz (Harvard University) on April 11, 2007, at the Materials Research Society Spring Meeting in San Francisco. The article describes how simple microfluidic devices can be used to control fluid flow and produce a variety of new materials. Based on the concepts of coaxial flow and hydrodynamically focused flow, us...

Bubbles, Drops and Vesicles: The Charm of Microfluidics

Segregation in desiccated sessile drops of biological fluids.

It is shown here that concurrence between advection and diffusion in a drying sessile drop of a biological fluid can produce spatial redistribution of albumen and salt. The result gives an explanation for the patterns observed in the dried drops of the biological fluids.